The purpose of the struts is not to carry weight. With the load concentrated toward the front of the bed, bumps tend to flex the truck frame in the middle. Any steel structure is a spring, and the frame can take this flexing. The issue is that it is a pretty good spring, and returns most of the energy it stores. There is virtually no damping. Over some roads, usually concrete with expansion joints, the bouncing can build up to very high levels. The struts soak up some energy with each bounce and keep the amplitude from building up.
Most of the flex is in the middle of the frame, the bed moves in relation to the cab. This creates a lot of motion between the cabover and the cab, making this the ideal place to put the damping. There is virtually no motion between the rear of the camper and the rear bumper/trailer hitch.
The struts do not restrain the cab from moving on the isolators. They do pass a small amount of frame/bed/camper vibration to the cab in theory. In practice I don't notice any difference in ride quality/noise, but I do note a marked reduction in the cab-over motion on rough roads.
To achieve this with a cushion between the cab and the camper, it should be some sort of energy adsorbent material...memory foam like they use on mattresses or something like silly putty. In grit ridden New Mexico this would result in paint damage in short order I would think.
Thank you for that well informed response. After a very uneventful (except for the scenery)3000 mile trip this summer with my Vanguard 995 (approx. 3k lbs) on my F250 I don't think I need to take any further action of any kind. Your expanation really fits with my experience. Thank you Kevbo